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most powerful hiv- attacking antibody yet has been constructed


a newly developed hiv antibody neutralizes 99 percent of virus strains, making it the most powerful yet found, according to a study led by duke university scientists.the broadly neutralizing antibody provides a base for an hiv the y to destroy a wide range of viruses in infected people, said  duke researcher barton f. haynes. it also provides insights into building an effective vaccine to prevent hiv infection.the study was published friday in science immunology. when published, it can be found at j.mp/99hiv. haynes was senior author. la tonya d. williams, also of duke, was first author.the team constructed the hybrid or chimeric antibody from pieces of two naturally occurring antibodies, haynes said in a video interview supplied by duke.one antibody was found in a patient who made an anti






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 96 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antibo






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 94 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antibo






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 104 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antib






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 92 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antibo






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 97 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antibo






'blocker' could help fight cocaine addiction


andrew norman, uc college of medicine professor, in his laboratory.(photo: provided) 104 connectlinkedinemailmorecincinnati — university of cincinnati researchers have developed an immunotherapy that could be the first fda-approved medication to block the effects of cocaine.cocaine has increasingly played a role in the opioid and heroin epidemic nationally. it's often a secondary drug choice of those who use heroin and prescription painkillers, which are synthetic opiates.andrew norman, a professor in the department of pharmacology and cell biophysics at the uc college of medicine, has led the development of an antibody that can block cocaine's effects on users.do you tell your kids about your past drug use?"this will not be a magic bullet," norman said. but, he added, the injectable antib






woman's rare genetic disorder could hold the key to weight loss


austin, texas -- abby solomon’s purse looks like a traveling pantry, full of sugary snacks.“my life basically revolves around food,” she said.and yet for all she eats, she’s in a constant battle with starvation.  abby solomon cbs news abby was born with a rare genetic disorder called neonatal progeroid syndrome. the mutation mangles noses and makes abby look prematurely old. it also prevents her body from making enough asprosin, a hormone that stimulates appetite. she’s not hungry but still needs to eat all the time. the food feeds her brain just enough glucose to keep her from passing out. but after a few bites, she feels full. abby consumes half the amount of normal calories for a woman her age; and at 5 feet 10 inches, weighs just 99 pounds.she’s eating, but not gaining weight.“i mean,






world clash - hero clan battle


brand new viking-action-strategy. only for true warriors: in this action packed strategy game, you will start with a small clan of vikings and battle for both glory and riches alongside unique and powerful heroes. transform your village into an impenetrable fortress and found an unconquerable kingdom. exciting free-to-play actionthere is always something to do - buildings have to be raised, heroes need to be trained and warriors have to be recruited. and of course there is a lot of loot to acquire. am your armies, attack your enemies and defend your fortress. win each clash with your enemies and emerge victorious from each battle. innovative hero-system with rpg-elementsgather powerful and magical heroes in this viking-fantasy game and emerge victorious from each battle. train them so t






off-duty castle rock police officer fatally shoots attacking dog on parker trail


an off-duty castle rock police officer, walking with his wife wednesday evening on a parker trail, shot and killed a dog that authorities say began attacking the couple.the incident happened about 5 p.m. on wednesday in the canterberry subdivision.the dog was shot twice, according to parker police. investigators did not say whether the officer used his duty weapon.“it’s my understanding that there’s not going to be any charges against the officer,” parker police officer sherry corcoran said. “however, there may be charges against the dog owner.”the parker police department said friday that an investigation into the case remains ongoing.






sketch


the most important part of any drawing application is arguably the drawing area, so we've just made sketch contain one big and infinitely large view with no palettes to be seen. that doesn't mean we've compromised on the tools though. sketch is a true vector editing application and has many powerful tools to manipulate those vectors. sketch has boolean operations that fully preserve your carefully constructed vectors down the individual curves. for optimal flexibility we have something unique; dynamic boolean on groups of vectors. but there is more; sketch has distortion tools as well as transformations, scissors and your truly innovative smart rotate which makes consecutive rotations truly easy and intuitive. the vector tool itself is intuitive and easy to use and our pen tool is an ex






b&o play debuts the powerful, portable beolit 17 wireless speaker


why it matters to you if you're looking for a portable wireless speaker to power your next part, b&o play's latest is one to watch.bluetooth speakers were initially meant to be portable at the expense of quality sound. now we’ve reached a place where the sound can be great and the speaker can weigh less than a truck. bang & olufsen brand b&o play has made several speakers on the larger side of portable that offer tremendous sound over the years, and now it has unveiled its most powerful yet in the beolit 17.if you’ve seen the beolit 12, which was released in 2012, or the beolit 15, released in 2015, the beolit 17 should look fairly familiar. award-winning designed cecilie manz designed both of those speakers, as well as the beolit 17. while it isn’t as rugged as some other speakers, this m






who will get first dibs on the powerful james webb space telescope?


nasa has issued solicitation for science projects using the long-awaited and incredibly powerful successor to hubble, which is scheduled to launch next year.






age of voyage - pirate's war


age of voyage is an oceanic adventure game. in the era of pirates, you can become the most powerful king through adventures and wars. you can strengthen your warships by exploring pirates' treasures in the ocean or plunder treasures by directly attacking other pirates. when you are in defense or attack, you need to win victory in the real-time battle by utilizing your strategies and tactics to ensure the gradual level up of your warships. tens of well-known pirate ships are waiting for your sailing. construct the world orderyou can create a new empire in the game by creating your own empire or joining a powerful oceanic empire with other pirate captains from each corner of the world. slg + card training playing methodsaside from the cl ic slg strategy playing method, an additional card






trial set for arizona man charged with ing websites


phoenix — a may 2 trial has been set for an apache junction man charged with ing into government websites in arizona and wisconsin.randall charles tucker has pleaded not guilty to charges of intentional damage to protected computers and threatening damage to protected computers for allegedly attacking municipal computer systems in march 2015 in the city of madison and two phoenix suburbs, chandler and mesa.he is accused of carrying out a cyberattack that e three days after a police shooting of an unarmed man in madison and interrupted communications equipment for emergency workers there.less than a week after the madison , authorities say tucker launched an attack on city websites in mesa and chandler.he also is accused of attacking the washington, d.c.-based news2share site in late 2014.






aurora home invaders point gun at babysitter


four men were accused of forcing their way into an alsip home and attacking several people in a dispute over an ex- friend, authorities said.the four men face multiple counts of home invasion, a cl x felony, according to cook county records.only abdullah alkhatib, 37, of bridgeview, is...four men were accused of forcing their way into an alsip home and attacking several people in a dispute over an ex- friend, authorities said.the four men face multiple counts of home invasion, a cl x felony, according to cook county records.only abdullah alkhatib, 37, of bridgeview, is... (nick swedberg)






goes-r/goes-16: a powerful weather satellite in pictures


the powerful new goes-r earth observation satellite will monitor the planet's weather, lightning and other phenomena like never before. see photos from the mission here.






what border walls look like around the world


erecting barriers between nations is nothing new. many countries have constructed them for protection or to stop migrants. here is a look at some countries that have created a barrier or plan to construct one along at least a portion of their border.u.s.-mexicovarious kinds of barriers along 653 miles of the 2,000-mile border.  here are the three most common types:turkey–syriaturkey’s barriers consist of 7-ton concrete slabs topped with razor wire.india–bangladeshindia’s barriers are lower to the ground, layered with posts and wire fence, and rolls of barbed wire.israel - west bankparts of israel’s border have high, concrete slabs topped with wire fencing.belfastin belfast, northern ireland, “peace lines,” are made of wood boards, or corrugated panels and posts topped with wire fencing.mor






senate punishes warren fore attacking fellow senator


powered by livefyre the opinions expressed in reader comments are those of the author only, and do not reflect the opinions of the seattle times.






terminally ill bradley lowery to be england mascot


image copyrightpaimage caption sunderland fan bradley took to the pitch at the stadium of light last year terminally ill football fanatic bradley lowery will be the england mascot at a world cup qualifier at wembley.bradley, five, was diagnosed with neuroblastoma in 2013 and only has months to live, his mother has said.the football association confirmed that he will lead the team on to the pitch when they play lithuania on 26 march.the news comes in the same week his family revealed he had developed a new tumour.last year, well-wishers raised hundreds of thousands of pounds to pay for antibody treatment in new york, but medics then found his cancer had grown and the family was informed his illness was terminal.he has since undergone "tumour-shrinking treatment" at newcastle's royal victori






terminally ill bradley lowery to be england mascot


image copyrightpaimage caption sunderland fan bradley took to the pitch at the stadium of light last year terminally ill football fanatic bradley lowery will be the england mascot at a world cup qualifier at wembley.bradley, five, was diagnosed with neuroblastoma in 2013 and only has months to live, his mother has said.the football association has announced that he will lead the team on to the pitch when they play lithuania on 26 march.the news comes in the same week his family revealed he had developed a new tumour.last year, well-wishers raised hundreds of thousands of pounds to pay for antibody treatment in new york, but medics then found his cancer had grown and the family was informed his illness was terminal.he has since undergone "tumour-shrinking treatment" at newcastle's royal vic






terminally ill bradley lowery to be england mascot


image copyrightpaimage caption sunderland fan bradley took to the pitch at the stadium of light last year terminally ill football fanatic bradley lowery will be the england mascot at a world cup qualifier at wembley.bradley, five, was diagnosed with neuroblastoma in 2013 and only has months to live, his mother has said.the football association confirmed that he will lead the team on to the pitch when they play lithuania on 26 march.the news comes in the same week his family revealed he had developed a new tumour.last year, well-wishers raised hundreds of thousands of pounds to pay for antibody treatment in new york, but medics then found his cancer had grown and the family was informed his illness was terminal.he has since undergone "tumour-shrinking treatment" at newcastle's royal victori






terminally ill bradley lowery to be england mascot


image copyrightpaimage caption sunderland fan bradley took to the pitch at the stadium of light last year terminally ill football fanatic bradley lowery will be the england mascot at a world cup qualifier at wembley.bradley, five, was diagnosed with neuroblastoma in 2013 and only has months to live, his mother has said.the football association has announced that he will lead the team onto the pitch when they play lithuania on 26 march.the news comes in the same week his family revealed he had developed a new tumour.last year, well-wishers raised hundreds of thousands of pounds to pay for antibody treatment in new york, but medics then found his cancer had grown and the family was informed his illness was terminal.he has since undergone "tumour-shrinking treatment" at newcastle's royal vict






israel set to raze west bank village


khan al ahmar, the west bank—halimeh zahayka runs a palestinian school here built in 2009 with walls of mud and old tires. soon she may have no building at all.last week, the israeli military deemed the entire village was constructed illegally, setting the stage for the school and other buildings here to be razed. a lawyer for the village said...






rise of zombie pro download


download download rise of zombie pro. get ready for an action of the killing frenzy. defend your gate from the revolting of zombie madness with deadly weapons like sword, saw, guns, grenade, bomb and many more. make use of multiple weapons that will help you kill the zombies, click on the special weapon atomic bomb to make the massive destroying damage. unlock and upgrade the new weapons in the store to stand with the powerful zombie bosses. rise of zombies is the hack-and-slash defense game, but the way to defend in this game is attacking. in a darkest night, the alien creature xeno queen makes her first invasion action to earth by releasing the virus into the graven town's graveyard. the zombies rise from the graves and heading to the graven town. the only one who can stop these zombie






‘how many jobs’ has trump created by attacking the media?


fox news host chris wallace pointed out to trump surrogate corey lewandowski on sunday that attacking the media does not further the president’s legislative agenda. “the reason we invited you one in the first place, i want to talk about the trump agenda with you,” wallace told lewandowski during an interview on fox news sunday. “these last couple of weeks of mr. trump’s first days in office have been dominated by attacks on the media and the intelligence community.”“do all of these attacks on the media and intelligence and opponents, does that get in the way of [donald trummp’s agenda]?” the fox host wondered. lewandowski argued that media reports about trump “were 100 percent factually inaccurate.”“why not just pursue his agenda?” wallace pressed, noting that trump had called the media a






manchester contacts nfl regarding stadium


local developer doug manchester has contacted nfl commissioner roger goodell expressing a desire to build a privately-financed stadium in mission valley.manchester, the former owner of the san diego union-tribune, told goodell he had “assembled a powerful group of associates” who will develop the land on which qualcomm stadium sits and “construct a new 70,000-seat stadium and surrounding development.”an nfl spokesman did not immediately respond to a request for comment on the letter. manchester declined to comment.significantly, the letter said the project could “provide an immediate alternative” for the raiders if their stadium proposal in las vegas falls through. the raiders maintain they are still working toward moving to las vegas despite two potential financial partners withdrawing. l






expect more gung-ho attacking in man city-monaco part ii


manchester, england (ap) — pep guardiola and leonardo jardim were up and down from their seats in the dugout, trying to get messages to their players but ultimately powerless to exert any control in a chaotic game that was unfolding before them.in the end, they were just swept along by it like everyone else.guardiola’s manchester city and jardim’s monaco served up a spectacular champions league match on tuesday, a dizzying eight-goal thriller that had everything: stunning goals, woeful defending, exquisite build-up play, a missed penalty, refereeing controversies.city came out on top, scoring three late goals in an 11-minute span to win 5-3, but both coaches agreed that soccer was the real winner.most read storiessave 75% on digital access today.“it was special, i cannot deny that,” guardi






here are foreign-born terrorists reporters can’t believe exist


when arguing with the left about matters of national security and terrorism, one becomes accustomed to their habitual moving of goal posts and artificial construction of sample sizes that deliberately exclude relevant cases.the most notorious example, of course, is the beloved “since 9/11…” canard, such as the oft-repeated although false claim that since 9/11 right-wing terrorists have killed more americans than islamic terrorists.the recent executive order by the trump administration on immigration led to an urgent desire to proclaim that there is no terrorism threat from immigrants. the most egregious example: a tweet from the new york times’ white house correspondent maggie haberman, who is also a cnn analyst. she posed the question, “other than san bernardino shootings, has there been






expect more gung-ho attacking in man city-monaco part ii


manchester, england — pep guardiola and leonardo jardim were up and down from their seats in the dugout, trying to get messages to their players but ultimately powerless to exert any control in a chaotic game that was unfolding before them.in the end, they were just swept along by it like everyone else.guardiola's manchester city and jardim's monaco served up a spectacular champions league match on tuesday, a dizzying eight-goal thriller that had everything: stunning goals, woeful defending, exquisite build-up play, a missed penalty, refereeing controversies.city came out on top, scoring three late goals in an 11-minute span to win 5-3, but both coaches agreed that soccer was the real winner."it was special, i cannot deny that," guardiola said.the game was a reflection of the attacking phi






prevailing wage bill will worsen housing crisis


california is experiencing a housing supply and affordability crisis with social and economic consequences for communities across the state. hard working families are feeling the pain as they are forced to go to extraordinary lengths to keep a roof over their head.that is why it is so hard to understand why assemblyman kansen chu (d-san jose) would believe that now is the time to inflate the cost of housing by as much as 37 percent. this is precisely what assembly bill 199 would do.ab 199 mandates the payment of prevailing wages on new privately constructed residential housing. this will translate into crippling construction costs that will drive rental and housing prices even higher.prevailing wage mandates from the california legislature have long been a goal of powerful construction uni






this 16-year-old canadian girl is responsible for the epic takedown of milo yian


milo yiannopoulos suffered a very public downfall this week when a clip surfaced of the conservative justifying pedophilia. behind it all was a 16-year-old canadian girl. “i see milo as this embodiment of the awfulness you see over the past few years with the general tilt of millennial conservatism,” she said in an interview with german lopez. she seems him as “more accurately described as anti-liberal than he would be conservative.”she heard yiannopoulos had been asked to speak at the conservative political action conference (cpac) outside of washington, d.c. this week, and she didn’t want to see the conservative movement turn to the anti-women, anti-muslim ideology she feels yiannopoulos embodies. it only took a few days once the clip surfaced for yiannopoulos to lose his job at breitbar






this 16-year-old canadian girl is responsible for the epic takedown of milo yian


milo yiannopoulos suffered a very public downfall this week when a clip surfaced of the conservative justifying pedophilia. behind it all was a 16-year-old canadian girl. “i see milo as this embodiment of the awfulness you see over the past few years with the general tilt of millennial conservatism,” she said in an interview with german lopez. she seems him as “more accurately described as anti-liberal than he would be conservative.”she heard yiannopoulos had been asked to speak at the conservative political action conference (cpac) outside of washington, d.c. this week, and she didn’t want to see the conservative movement turn to the anti-women, anti-muslim ideology she feels yiannopoulos embodies. it only took a few days once the clip surfaced for yiannopoulos to lose his job at breitbar






man charged with attacking children at near north side school playground


a st. louis man is accused of walking into a near north side playground and battering four children and a school administrator, authorities said. tasewell dugger, 46, of the 9200 block of ellision drive in st. louis, was charged with four counts of aggravated battery of a child under the age of 13 and criminal tresp , chicago police said. he was expected to appear thursday in bond court.  as first graders at a gold coast elementary school played outside during recess tuesday, a 46-year-old st. louis man somehow got onto the playground and beat four students, prosecutors said thursday.the bizarre incident at the east pus of ogden international school of chicago, an elementary school at 24 w. walton st., began at 11 a.m. tuesday when tasewell dugger somehow got past a wrought-iron fence that






colorado zoos work together to save baby giraffe


closeskip in skipxembedxshare the denver zoo gained a new member when dobby was born feb. 28 after a surprise pregnancy. the baby giraffe soon needed a little help fighting off infection. jennifer heftydobby was born after a surprise pregnancy.(photo: denver zoo) 7 connectlinkedinemailmoretwo colorado zoos are to thank for saving a giraffe calf named doby.dobby was born feb. 28 after a surprise pregnancy. (mom kipele janie was on birth control.) he came out small for a newborn, 5 feet tall and 73 pounds. yes, that's small for a newborn giraffe.mom had trouble nursing the calf, who wasn't wasn’t receiving enough “infection-fighting proteins" in his first few days of life, the denver zoo said in a post on facebook. thankfully, staff at the nearby cheyenne mountain zoo donated a plasma transf






57% off anker led water-resistant rechargeable 1300 lumen flashlight - deal aler


the high-performance cree led xm-l2 chip delivers 50,000 hours of intense brightness at a true 1300 lumens. sweep bright light beyond the length of two football fields. the anker bolder torch has a full range of light modes for every situation: a powerful high-beam, balanced medium-beam, energy-saving & less dazzling low-beam, high-visibility strobe, and emergency sos. it's rechargeable battery generates 6 hours of undiminishing light on a charge. it's body is constructed of professional durable materials, and is ip67 rated for water resistance. rated 4.5 out of 5 stars from over 100 people on amazon (84% rate a full 5 -- see reviews here), its $112 list price is reduced 57% to just $47.99. see this deal on amazon.this story, "57% off anker led water-resistant rechargeable 1300 lumen f






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download download picsart is a powerful photo editing apps for snapchat of any filters. it contains the vast editing kit of tools for basic and advanced retouching of your photos. make each your pics a perfect complete art using a wide range of picsart effects, filters, text editing and color enhancement tools and a lot of other ready-to-use features. picsart has a simple design with a powerful collage maker and an amazing photo editor. discover new free pics art. including photo editing, collage, drawing and picsart remix pics art is easy to use and powerful photo editor and collage maker for sharing on snapchat. add emoticons to your photos with emojis smiles and popular tags.






why the cia is using your tvs, smartphones and cars for spying


the latest revelations about the u.s. government's powerful hacking tools potentially take surveillance right into the homes and hip pockets of billions of technology users worldwide, showing how a remarkable variety of everyday devices can be turned to spy on their owners.televisions, smartphones and even anti-virus software are all vulnerable to cia hacking, according to wikileaks documents released tuesday. the capabilities described include recording the sounds, images and private text messages of users, even when they resort to encrypted apps to communicate.while many of the attack technologies had been previously discussed at cybersecurity conferences, experts were startled to see evidence that the cia had turned so many theoretical vulnerabilities into functioning attack tools again






patchogue village continues its growth spurt


advertisement | advertise on newsdaykimberly burkart and nicole ramirez, managers at smallcakes cupcakery and creamery in patchogue, on tuesday, feb. 28, 2017. (credit: newsday / thomas a. ferrara) new retail stores and restaurants have opened in downtown patchogue, continuing the revival of main street as a major business draw and tourist attraction.most of the new businesses have opened since november and more are expected by summer.patchogue has seen a major revitalization in recent years, with more than 700 apartments constructed downtown that have brought in new residents,...






patchogue village continues its growth spurt


advertisement | advertise on newsdaykimberly burkart and nicole ramirez, managers at smallcakes cupcakery and creamery in patchogue, on tuesday, feb. 28, 2017. (credit: newsday / thomas a. ferrara) new retail stores and restaurants have opened in downtown patchogue, continuing the revival of main street as a major business draw and tourist attraction.most of the new businesses have opened since november and more are expected by summer.patchogue has seen a major revitalization in recent years, with more than 700 apartments constructed downtown that have brought in new residents,...






man detained at lax and deported to iran, but federal judge in l.a. orders retur


captioncurves, craftsmanship and cl | 2017 grand national roadster show in pomonathirteen custom cars will compete for the “america's most beautiful roadster” award, vying for a 9-foot-tall trophy and $10,000 in prize money. (gina ferazzi / los angeles times)thirteen custom cars will compete for the “america's most beautiful roadster” award, vying for a 9-foot-tall trophy and $10,000 in prize money. (gina ferazzi / los angeles times)